The settlements were meager and consisted of Cape Cod fishermen and their families, who were often left to fend for themselves in a harsh and lonely place. There's no evidence that there was a settlement on this island then. But its cove was well known by New England fishermen as a safe harbour from storms, and a good place to anchor and repair their boats.
Note the presence of the Mikmak or Cape Sable Indians indicated on the map. There's no direct evidence yet of their presence here on the island but it could well have been a place of seasonal encampments, perhaps even as late as 1755.
Image is courtesy of NSARM.