There is a three-branched harbour in about the centre of the coastline. That is probably what is now called Shelburne Harbour, or maybe Shelburne Harbour and Jordan Bay shown together as one. Champlain seems to have labelled it Port d'Negro. There's an island in the harbour, which could be what's now called McNutt's. Just to the south of it, in its more-or-less correct place, is Cape Negro.
It gives me the shivers to think that Samuel Champlain sailed past this place, even in the fog.
Thanks to Terry Deveau for sharing this map with me. The original is in the US Library of Congress.